| NAME | TEAM | W | L | T | PF | PA | +/- | Draft |
| Patrick Mahomes | SD | 9 | 2 | 1 | 539 | 396 | 143 | 116 |
| Drew Brees | ANC | 6 | 7 | 1 | 467 | 413 | 54 | 48 |
| Matt Ryan | SH | 7 | 4 | 1 | 429 | 368 | 61 | 97 |
| Andrew Luck | ATL | 9 | 3 | 0 | 425 | 351 | 74 | 59 |
| Todd Gurley | SD | 13 | 1 | 0 | 386 | 172 | 214 | 1 |
| Deshaun Watson | SF | 5 | 9 | 0 | 377 | 465 | -88 | 51 |
| Christian McCaffrey | CTR | 10 | 4 | 0 | 371 | 193 | 178 | 18 |
| Ben Roethlisberger | FW | 3 | 6 | 1 | 369 | 395 | -26 | 88 |
| Ezekiel Elliott | DET | 9 | 5 | 0 | 365 | 263 | 102 | 3 |
| Aaron Rodgers | CTR | 9 | 4 | 0 | 364 | 281 | 83 | 29 |
| Jared Goff | LAB | 5 | 5 | 0 | 362 | 362 | 0 | 120 |
| Saquon Barkley | ATL | 11 | 3 | 0 | 361 | 244 | 117 | 5 |
| Tom Brady | TB | 8 | 5 | 0 | 345 | 298 | 47 | 39 |
| Carson Wentz | DET | 5 | 7 | 0 | 341 | 396 | -55 | 68 |
| James Conner | ATL | 9 | 4 | 0 | 333 | 202 | 131 | 118 |
| Tyreek Hill | CTR | 7 | 6 | 0 | 320 | 213 | 107 | 42 |
| Alvin Kamara | CTR | 7 | 6 | 1 | 305 | 245 | 60 | 7 |
| Adam Thielen | ANC | 10 | 3 | 1 | 302 | 222 | 80 | 34 |
| Julio Jones | SF | 8 | 5 | 1 | 301 | 230 | 71 | 9 |
| Travis Kelce | ANC | 11 | 3 | 0 | 294 | 153 | 141 | 23 |
| Antonio Brown | FW | 8 | 5 | 1 | 289 | 231 | 58 | 6 |
| Melvin Gordon | ANC | 8 | 2 | 0 | 284 | 195 | 89 | 10 |
| Kareem Hunt | DEN | 8 | 4 | 0 | 284 | 269 | 15 | 8 |
| DeAndre Hopkins | ND | 9 | 4 | 1 | 276 | 214 | 62 | 11 |
| JuJu Smith-Schuster | DEN | 9 | 4 | 1 | 270 | 238 | 32 | 57 |
| Michael Thomas | DET | 9 | 5 | 0 | 262 | 215 | 47 | 22 |
| Zach Ertz | DET | 10 | 4 | 0 | 235 | 149 | 86 | 28 |
| Joe Mixon | SF | 8 | 4 | 0 | 234 | 196 | 38 | 19 |
| Mike Evans | SH | 7 | 5 | 2 | 226 | 199 | 27 | 27 |
| David Johnson | SF | 6 | 5 | 2 | 220 | 206 | 14 | 4 |
| Odell Beckham | TB | 5 | 7 | 0 | 220 | 208 | 12 | 14 |
| James White | SH | 7 | 7 | 0 | 214 | 222 | -8 | 162 |
| Cam Newton | ND | 3 | 4 | 0 | 211 | 215 | -4 | 55 |
| Emmanuel Sanders | DEN | 8 | 5 | 0 | 190 | 144 | 46 | 125 |
| Jameis Winston | DEN | 2 | 4 | 0 | 188 | 194 | -6 | 169 |
| Brandin Cooks | ATL | 5 | 6 | 0 | 180 | 148 | 32 | 63 |
| George Kittle | SD | 7 | 5 | 0 | 174 | 115 | 59 | 93 |
| Keenan Allen | SH | 5 | 4 | 0 | 171 | 158 | 13 | 13 |
| Robert Woods | ND | 6 | 5 | 0 | 166 | 151 | 15 | 64 |
| A.J. Green | SD | 6 | 5 | 0 | 161 | 148 | 13 | 26 |
| Davante Adams | ANC | 3 | 5 | 0 | 161 | 168 | -7 | 24 |
| Chicago D | ANC | 9 | 1 | 2 | 158 | 73 | 85 | FA |
| Amari Cooper | LAB | 6 | 5 | 0 | 154 | 103 | 51 | 38 |
| Jarvis Landry | CTR | 5 | 7 | 1 | 144 | 176 | -32 | 52 |
| Tyler Boyd | SF | 4 | 5 | 1 | 138 | 141 | -3 | FA |
| LeSean McCoy | FW | 5 | 4 | 2 | 138 | 165 | -27 | 16 |
| Golden Tate | DET | 5 | 5 | 1 | 138 | 171 | -33 | 50 |
| Mark Ingram | SD | 5 | 4 | 0 | 136 | 68 | 68 | 75 |
| Ka'imi Fairbairn | LAB | 10 | 3 | 1 | 135 | 115 | 20 | FA |
| Adrian Peterson | ANC | 1 | 9 | 1 | 135 | 242 | -107 | FA |
| Jared Cook | CTR | 6 | 7 | 0 | 134 | 97 | 37 | 129 |
| Justin Tucker | TB | 7 | 5 | 2 | 134 | 129 | 5 | 85 |
| Wil Lutz | ANC | 7 | 6 | 1 | 133 | 105 | 28 | 149 |
| Stefon Diggs | TB | 5 | 4 | 0 | 127 | 176 | -49 | 47 |
| Lamar Miller | TB | 4 | 6 | 0 | 127 | 197 | -70 | 53 |
| Harrison Butker | DEN | 9 | 5 | 0 | 126 | 119 | 7 | 143 |
| T.Y. Hilton | TB | 3 | 3 | 0 | 126 | 120 | 6 | 33 |
| Mason Crosby | SD | 6 | 7 | 1 | 125 | 104 | 21 | 175 |
| Houston D | ATL | 7 | 6 | 0 | 122 | 115 | 7 | 105 |
| Stephen Gostkowski | CTR | 9 | 5 | 0 | 121 | 107 | 14 | 119 |
| Josh Gordon | ATL | 4 | 5 | 1 | 117 | 150 | -33 | 36 |
| Los Angeles Rams D | ND | 8 | 4 | 0 | 114 | 92 | 22 | 98 |
| Ryan Fitzpatrick | DEN | 2 | 2 | 0 | 114 | 103 | 11 | FA |
| Sony Michel | FW | 2 | 7 | 0 | 113 | 199 | -86 | 100 |
| Jimmy Graham | FW | 9 | 5 | 0 | 112 | 109 | 3 | 56 |
| Andy Dalton | ND | 1 | 4 | 0 | 110 | 160 | -50 | FA |
| Eric Ebron | ND | 5 | 3 | 0 | 109 | 95 | 14 | FA |
| Pittsburgh D | SF | 8 | 6 | 0 | 108 | 92 | 16 | 165 |
| Matt Prater | ND | 6 | 7 | 1 | 108 | 117 | -9 | 139 |
| New England D | SH | 7 | 7 | 0 | 107 | 109 | -2 | 128 |
| Will Fuller | FW | 3 | 3 | 1 | 106 | 91 | 15 | 102 |
| Russell Wilson | DEN | 1 | 4 | 0 | 106 | 163 | -57 | 43 |
| Greg Zuerlein | ATL | 6 | 3 | 2 | 103 | 73 | 30 | 124 |
| Phillip Lindsay | FW | 4 | 3 | 0 | 103 | 89 | 14 | FA |
| Los Angeles Chargers D | TB | 7 | 6 | 1 | 103 | 99 | 4 | 112 |
| Alex Collins | DET | 4 | 7 | 0 | 103 | 177 | -74 | 46 |
| Jordan Howard | TB | 4 | 7 | 0 | 101 | 214 | -113 | 21 |
| Jacksonville D | DET | 7 | 7 | 0 | 98 | 124 | -26 | 84 |
| Rob Gronkowski | DEN | 4 | 6 | 0 | 96 | 134 | -38 | 20 |
| Baker Mayfield | FW | 2 | 2 | 0 | 96 | 150 | -54 | FA |
| Trey Burton | TB | 8 | 6 | 0 | 95 | 71 | 24 | 81 |
| Cleveland D | LAB | 8 | 5 | 0 | 95 | 93 | 2 | FA |
| Leonard Fournette | ND | 3 | 3 | 0 | 94 | 75 | 19 | 15 |
| Jake Elliott | FW | 5 | 8 | 1 | 92 | 105 | -13 | 144 |
| Jordan Reed | SH | 6 | 8 | 0 | 92 | 141 | -49 | 86 |
| Marlon Mack | ND | 2 | 3 | 0 | 92 | 148 | -56 | 71 |
| Alex Smith | ND | 1 | 3 | 0 | 91 | 155 | -64 | 117 |
| Aaron Jones | TB | 4 | 3 | 0 | 90 | 98 | -8 | 145 |
| Marshawn Lynch | SF | 4 | 3 | 0 | 85 | 87 | -2 | 44 |
| Tevin Coleman | LAB | 3 | 6 | 0 | 85 | 116 | -31 | 82 |
| Kenny Golladay | LAB | 2 | 7 | 0 | 84 | 142 | -58 | FA |
| David Njoku | ATL | 3 | 11 | 0 | 81 | 160 | -79 | 91 |
| Kyle Rudolph | LAB | 5 | 9 | 0 | 79 | 134 | -55 | 61 |
| New York Jets D | FW | 4 | 9 | 0 | 78 | 97 | -19 | FA |
| Matt Bryant | DET | 5 | 7 | 2 | 78 | 105 | -27 | 132 |
| Tarik Cohen | ND | 2 | 3 | 0 | 76 | 87 | -11 | 66 |
| Kerryon Johnson | DEN | 3 | 4 | 0 | 73 | 75 | -2 | 54 |
| Graham Gano | SH | 4 | 7 | 1 | 72 | 82 | -10 | FA |
| Dalvin Cook | SH | 1 | 3 | 1 | 70 | 100 | -30 | 12 |
| Larry Fitzgerald | FW | 3 | 3 | 1 | 61 | 97 | -36 | 35 |
| Matthew Stafford | DET | 1 | 1 | 0 | 60 | 55 | 5 | 114 |
| Dan Bailey | SF | 2 | 9 | 0 | 60 | 104 | -44 | 171 |
| Philadelphia D | SD | 2 | 8 | 1 | 56 | 94 | -38 | 104 |
| Nick Chubb | LAB | 2 | 1 | 0 | 55 | 48 | 7 | 106 |
| Kirk Cousins | SD | 1 | 1 | 0 | 55 | 63 | -8 | 70 |
| T.J. Yeldon | ND | 1 | 3 | 0 | 51 | 66 | -15 | FA |
| Minnesota D | CTR | 2 | 4 | 0 | 50 | 61 | -11 | 95 |
| Jimmy Garoppolo | ATL | 1 | 1 | 0 | 50 | 81 | -31 | 113 |
| Greg Olsen | SF | 5 | 3 | 0 | 50 | 90 | -40 | 65 |
| Cooper Kupp | SD | 3 | 1 | 0 | 48 | 38 | 10 | 142 |
| Demaryius Thomas | LAB | 2 | 4 | 0 | 48 | 86 | -38 | 32 |
| Carlos Hyde | LAB | 2 | 2 | 0 | 47 | 71 | -24 | 76 |
| Chris Carson | DET | 1 | 2 | 0 | 45 | 52 | -7 | 99 |
| Giovani Bernard | FW | 1 | 1 | 0 | 44 | 34 | 10 | 123 |
| Baltimore D | CTR | 3 | 4 | 0 | 44 | 53 | -9 | 109 |
| Tyrod Taylor | LAB | 0 | 2 | 0 | 44 | 73 | -29 | 121 |
| Indianapolis D | DEN | 2 | 4 | 1 | 43 | 46 | -3 | FA |
| Calvin Ridley | ATL | 3 | 2 | 0 | 42 | 59 | -17 | FA |
| Marvin Jones | SD | 0 | 5 | 1 | 40 | 97 | -57 | 58 |
| Julian Edelman | DET | 1 | 1 | 1 | 38 | 36 | 2 | 90 |
| Robbie Gould | SF | 1 | 4 | 0 | 38 | 46 | -8 | 176 |
| Seattle D | CTR | 2 | 0 | 0 | 33 | 10 | 23 | FA |
| Dak Prescott | TB | 0 | 1 | 0 | 33 | 37 | -4 | 127 |
| Jay Ajayi | DEN | 0 | 2 | 0 | 33 | 41 | -8 | 30 |
| Allen Robinson | SH | 0 | 5 | 0 | 33 | 125 | -92 | 45 |
| Spencer Ware | DEN | 1 | 1 | 0 | 32 | 31 | 1 | 159 |
| Austin Ekeler | ANC | 1 | 2 | 0 | 31 | 35 | -4 | 167 |
| Austin Hooper | DEN | 1 | 3 | 0 | 31 | 58 | -27 | FA |
| Nelson Agholor | ND | 1 | 2 | 0 | 30 | 38 | -8 | 161 |
| Mitchell Trubisky | LAB | 1 | 0 | 0 | 28 | 12 | 16 | 150 |
| Royce Freeman | LAB | 1 | 2 | 0 | 28 | 40 | -12 | 40 |
| Tyler Lockett | DEN | 0 | 2 | 0 | 28 | 52 | -24 | FA |
| Peyton Barber | LAB | 0 | 3 | 0 | 28 | 78 | -50 | 147 |
| Jack Doyle | ND | 2 | 3 | 0 | 25 | 39 | -14 | 92 |
| Carolina D | CTR | 1 | 1 | 1 | 23 | 14 | 9 | 174 |
| Nyheim Hines | ND | 0 | 2 | 0 | 21 | 67 | -46 | FA |
| Kenyan Drake | SH | 1 | 5 | 0 | 21 | 95 | -74 | 31 |
| D.J. Moore | SD | 0 | 1 | 1 | 20 | 32 | -12 | FA |
| Ty Montgomery | SD | 2 | 1 | 0 | 19 | 12 | 7 | 153 |
| Washington D | DEN | 1 | 3 | 0 | 19 | 34 | -15 | FA |
| Evan Engram | SF | 1 | 1 | 0 | 18 | 10 | 8 | 49 |
| Sammy Watkins | LAB | 1 | 3 | 0 | 18 | 31 | -13 | 80 |
| Joe Flacco | CTR | 0 | 1 | 0 | 18 | 36 | -18 | FA |
| C.J. Anderson | SH | 0 | 5 | 1 | 18 | 99 | -81 | 110 |
| Buffalo D | SD | 1 | 2 | 0 | 16 | 29 | -13 | FA |
| Antonio Callaway | ATL | 0 | 2 | 0 | 16 | 54 | -38 | FA |
| Jeff Wilson | ATL | 1 | 0 | 0 | 14 | 13 | 1 | FA |
| Jaylen Samuels | ND | 0 | 1 | 0 | 13 | 14 | -1 | FA |
| Gus Edwards | SD | 0 | 1 | 0 | 13 | 39 | -26 | FA |
| LeGarrette Blount | DEN | 0 | 1 | 1 | 13 | 49 | -36 | 134 |
| Detroit D | FW | 0 | 1 | 0 | 12 | 15 | -3 | 170 |
| Corey Davis | CTR | 1 | 0 | 0 | 11 | 5 | 6 | 78 |
| Theo Riddick | DEN | 1 | 0 | 0 | 10 | 3 | 7 | FA |
| Cairo Santos | ATL | 1 | 0 | 0 | 10 | 9 | 1 | FA |
| Courtland Sutton | SD | 1 | 2 | 0 | 9 | 15 | -6 | FA |
| Tyler Eifert | SF | 0 | 1 | 0 | 9 | 18 | -9 | 155 |
| Dallas D | ND | 0 | 1 | 0 | 9 | 19 | -10 | FA |
| Latavius Murray | ATL | 0 | 0 | 1 | 8 | 8 | 0 | FA |
| Benjamin Watson | SF | 1 | 1 | 0 | 6 | 10 | -4 | FA |
| Tennessee D | ATL | 1 | 0 | 0 | 5 | 2 | 3 | FA |
| Jamison Crowder | CTR | 1 | 0 | 0 | 5 | 4 | 1 | 131 |
| Delanie Walker | CTR | 0 | 1 | 0 | 5 | 10 | -5 | 69 |
| Denver D | CTR | 0 | 1 | 0 | 5 | 17 | -12 | FA |
| Keelan Cole | ATL | 0 | 1 | 0 | 5 | 34 | -29 | FA |
| Arizona D | ND | 1 | 0 | 0 | 4 | 1 | 3 | FA |
| Dion Lewis | ATL | 0 | 0 | 1 | 4 | 4 | 0 | 72 |
| Devonta Freeman | SD | 0 | 1 | 0 | 4 | 5 | -1 | 17 |
| Quincy Enunwa | FW | 0 | 1 | 0 | 4 | 10 | -6 | FA |
| Adam Humphries | SD | 0 | 1 | 0 | 4 | 19 | -15 | FA |
| Mike Davis | LAB | 0 | 1 | 0 | 4 | 32 | -28 | FA |
| Justin Jackson | ANC | 0 | 1 | 0 | 3 | 11 | -8 | FA |
| Isaiah Crowell | DEN | 0 | 1 | 0 | 3 | 17 | -14 | 67 |
| Chris Boswell | SH | 0 | 2 | 0 | 3 | 18 | -15 | 138 |
| C.J. Uzomah | SF | 0 | 1 | 0 | 3 | 21 | -18 | FA |
| Derrick Henry | ND | 0 | 0 | 1 | 2 | 2 | 0 | 41 |
| John Brown | ATL | 1 | 1 | 0 | 2 | 17 | -15 | FA |
| Alfred Morris | LAB | 0 | 2 | 0 | 2 | 20 | -18 | FA |
| Ryan Grant | LAB | 0 | 1 | 0 | 2 | 42 | -40 | FA |
| Geronimo Allison | SD | 0 | 1 | 0 | 1 | 7 | -6 | FA |
| Jordan Wilkins | ND | 0 | 1 | 0 | 1 | 15 | -14 | 172 |
| Chris Hogan | LAB | 0 | 1 | 0 | 1 | 20 | -19 | 73 |
| DeVante Parker | TB | 0 | 1 | 0 | 0 | 1 | -1 | 168 |
| New Orleans D | LAB | 0 | 1 | 0 | 0 | 13 | -13 | 160 |
| Jesse James | ND | 0 | 1 | 0 | 0 | 15 | -15 | FA |
| Doug Baldwin | ATL | 0 | 1 | 0 | 0 | 19 | -19 | 37 |
| O.J. Howard | SD | 0 | 2 | 0 | 0 | 19 | -19 | 130 |
| 647 | 647 | 50 | 20150 | 20150 | 0 | |||
| 1344 |