| NAME | TEAM | W | L | T | PF | PA | +/- | Draft |
| Patrick Mahomes | SD | 11 | 3 | 1 | 623 | 477 | 146 | 116 |
| Matt Ryan | SH | 9 | 5 | 1 | 530 | 464 | 66 | 97 |
| Drew Brees | ANC | 6 | 9 | 1 | 507 | 460 | 47 | 48 |
| Andrew Luck | ATL | 12 | 3 | 0 | 505 | 392 | 113 | 59 |
| Deshaun Watson | SF | 8 | 9 | 0 | 485 | 518 | -33 | 51 |
| Ben Roethlisberger | FW | 4 | 8 | 1 | 460 | 486 | -26 | 88 |
| Aaron Rodgers | CTR | 10 | 6 | 0 | 446 | 346 | 100 | 29 |
| Christian McCaffrey | CTR | 13 | 4 | 0 | 440 | 202 | 238 | 18 |
| Jared Goff | LAB | 6 | 6 | 1 | 438 | 429 | 9 | 120 |
| Todd Gurley | SD | 14 | 1 | 0 | 419 | 177 | 242 | 1 |
| Saquon Barkley | ATL | 13 | 4 | 0 | 418 | 290 | 128 | 5 |
| Ezekiel Elliott | DET | 9 | 8 | 0 | 405 | 323 | 82 | 3 |
| Tom Brady | TB | 9 | 6 | 0 | 403 | 363 | 40 | 39 |
| DeAndre Hopkins | ND | 12 | 4 | 1 | 369 | 246 | 123 | 11 |
| Tyreek Hill | CTR | 8 | 8 | 0 | 365 | 257 | 108 | 42 |
| Julio Jones | SF | 10 | 6 | 1 | 357 | 262 | 95 | 9 |
| Alvin Kamara | CTR | 8 | 7 | 1 | 347 | 291 | 56 | 7 |
| Antonio Brown | FW | 9 | 6 | 2 | 344 | 271 | 73 | 6 |
| Carson Wentz | DET | 5 | 7 | 0 | 341 | 396 | -55 | 68 |
| James Conner | ATL | 9 | 4 | 0 | 333 | 202 | 131 | 118 |
| Travis Kelce | ANC | 12 | 5 | 0 | 326 | 189 | 137 | 23 |
| Adam Thielen | ANC | 10 | 6 | 1 | 319 | 278 | 41 | 34 |
| JuJu Smith-Schuster | DEN | 9 | 6 | 2 | 312 | 302 | 10 | 57 |
| Michael Thomas | DET | 10 | 7 | 0 | 309 | 272 | 37 | 22 |
| Melvin Gordon | ANC | 9 | 3 | 0 | 301 | 219 | 82 | 10 |
| Mike Evans | SH | 10 | 5 | 2 | 295 | 222 | 73 | 27 |
| Joe Mixon | SF | 11 | 4 | 0 | 295 | 233 | 62 | 19 |
| Kareem Hunt | DEN | 8 | 4 | 0 | 284 | 269 | 15 | 8 |
| Zach Ertz | DET | 11 | 5 | 1 | 276 | 166 | 110 | 28 |
| David Johnson | SF | 6 | 7 | 2 | 247 | 255 | -8 | 4 |
| James White | SH | 8 | 9 | 0 | 245 | 270 | -25 | 162 |
| Jameis Winston | DEN | 3 | 4 | 0 | 234 | 230 | 4 | 169 |
| George Kittle | SD | 10 | 5 | 0 | 221 | 142 | 79 | 93 |
| Odell Beckham | TB | 5 | 7 | 0 | 220 | 208 | 12 | 14 |
| Brandin Cooks | ATL | 6 | 8 | 0 | 218 | 209 | 9 | 63 |
| Cam Newton | ND | 3 | 5 | 0 | 216 | 239 | -23 | 55 |
| Robert Woods | ND | 8 | 5 | 1 | 207 | 162 | 45 | 64 |
| Davante Adams | ANC | 5 | 5 | 0 | 207 | 170 | 37 | 24 |
| Emmanuel Sanders | DEN | 8 | 5 | 0 | 190 | 144 | 46 | 125 |
| Chicago D | ANC | 12 | 1 | 2 | 184 | 90 | 94 | FA |
| Keenan Allen | SH | 5 | 5 | 0 | 171 | 161 | 10 | 13 |
| Ka'imi Fairbairn | LAB | 12 | 4 | 1 | 169 | 135 | 34 | FA |
| T.Y. Hilton | TB | 4 | 4 | 1 | 168 | 155 | 13 | 33 |
| Amari Cooper | LAB | 7 | 6 | 1 | 166 | 114 | 52 | 38 |
| Justin Tucker | TB | 9 | 6 | 2 | 166 | 152 | 14 | 85 |
| Russell Wilson | DEN | 2 | 5 | 0 | 166 | 235 | -69 | 43 |
| A.J. Green | SD | 6 | 5 | 0 | 161 | 148 | 13 | 26 |
| Stefon Diggs | TB | 7 | 4 | 1 | 159 | 202 | -43 | 47 |
| Jarvis Landry | CTR | 6 | 8 | 1 | 154 | 202 | -48 | 52 |
| Mark Ingram | SD | 5 | 6 | 0 | 152 | 93 | 59 | 75 |
| Sony Michel | FW | 5 | 7 | 0 | 150 | 207 | -57 | 100 |
| Wil Lutz | ANC | 7 | 9 | 1 | 149 | 134 | 15 | 149 |
| Mason Crosby | SD | 8 | 8 | 1 | 148 | 113 | 35 | 175 |
| Harrison Butker | DEN | 10 | 7 | 0 | 148 | 163 | -15 | 143 |
| Tyler Boyd | SF | 4 | 6 | 1 | 147 | 155 | -8 | FA |
| LeSean McCoy | FW | 5 | 5 | 2 | 147 | 175 | -28 | 16 |
| Houston D | ATL | 7 | 9 | 0 | 146 | 159 | -13 | 105 |
| Jordan Howard | TB | 6 | 7 | 0 | 145 | 230 | -85 | 21 |
| Los Angeles Rams D | ND | 10 | 4 | 1 | 142 | 114 | 28 | 98 |
| Chris Carson | DET | 4 | 2 | 0 | 140 | 87 | 53 | 99 |
| Jared Cook | CTR | 8 | 7 | 1 | 140 | 101 | 39 | 129 |
| Stephen Gostkowski | CTR | 10 | 7 | 0 | 139 | 135 | 4 | 119 |
| Golden Tate | DET | 5 | 5 | 1 | 138 | 171 | -33 | 50 |
| Jacksonville D | DET | 9 | 7 | 1 | 137 | 149 | -12 | 84 |
| Adrian Peterson | ANC | 1 | 9 | 1 | 135 | 242 | -107 | FA |
| Greg Zuerlein | ATL | 8 | 3 | 3 | 134 | 100 | 34 | 124 |
| Matt Prater | ND | 7 | 9 | 1 | 134 | 148 | -14 | 139 |
| Los Angeles Chargers D | TB | 8 | 7 | 2 | 132 | 119 | 13 | 112 |
| Pittsburgh D | SF | 9 | 8 | 0 | 127 | 115 | 12 | 165 |
| Dalvin Cook | SH | 3 | 4 | 1 | 127 | 163 | -36 | 12 |
| Lamar Miller | TB | 4 | 7 | 0 | 127 | 202 | -75 | 53 |
| Marlon Mack | ND | 3 | 4 | 0 | 126 | 185 | -59 | 71 |
| Tevin Coleman | LAB | 5 | 7 | 0 | 125 | 137 | -12 | 82 |
| Eric Ebron | ND | 6 | 4 | 1 | 123 | 108 | 15 | FA |
| Jimmy Graham | FW | 11 | 6 | 0 | 120 | 117 | 3 | 56 |
| Jake Elliott | FW | 6 | 10 | 1 | 120 | 134 | -14 | 144 |
| Kenny Golladay | LAB | 3 | 8 | 0 | 118 | 170 | -52 | FA |
| Josh Gordon | ATL | 4 | 6 | 1 | 118 | 173 | -55 | 36 |
| Kyle Rudolph | LAB | 6 | 10 | 1 | 116 | 146 | -30 | 61 |
| Ryan Fitzpatrick | DEN | 2 | 2 | 0 | 114 | 103 | 11 | FA |
| Cleveland D | LAB | 9 | 5 | 2 | 112 | 107 | 5 | FA |
| Phillip Lindsay | FW | 5 | 4 | 0 | 112 | 116 | -4 | FA |
| Andy Dalton | ND | 1 | 4 | 0 | 110 | 160 | -50 | FA |
| New England D | SH | 7 | 7 | 0 | 107 | 109 | -2 | 128 |
| Will Fuller | FW | 3 | 3 | 1 | 106 | 91 | 15 | 102 |
| Matthew Stafford | DET | 2 | 3 | 0 | 106 | 122 | -16 | 114 |
| Matt Bryant | DET | 6 | 8 | 3 | 106 | 130 | -24 | 132 |
| Trey Burton | TB | 8 | 7 | 0 | 103 | 105 | -2 | 81 |
| Alex Collins | DET | 4 | 7 | 0 | 103 | 177 | -74 | 46 |
| David Njoku | ATL | 3 | 14 | 0 | 103 | 221 | -118 | 91 |
| Larry Fitzgerald | FW | 4 | 4 | 2 | 100 | 133 | -33 | 35 |
| Rob Gronkowski | DEN | 4 | 8 | 1 | 100 | 142 | -42 | 20 |
| Leonard Fournette | ND | 3 | 4 | 0 | 99 | 108 | -9 | 15 |
| Tarik Cohen | ND | 3 | 5 | 0 | 99 | 160 | -61 | 66 |
| Nick Chubb | LAB | 3 | 3 | 0 | 98 | 83 | 15 | 106 |
| New York Jets D | FW | 6 | 10 | 0 | 97 | 104 | -7 | FA |
| Baker Mayfield | FW | 2 | 2 | 0 | 96 | 150 | -54 | FA |
| Jordan Reed | SH | 6 | 8 | 0 | 92 | 141 | -49 | 86 |
| Alex Smith | ND | 1 | 3 | 0 | 91 | 155 | -64 | 117 |
| Aaron Jones | TB | 4 | 4 | 0 | 90 | 102 | -12 | 145 |
| Julian Edelman | DET | 4 | 1 | 1 | 89 | 57 | 32 | 90 |
| Dan Bailey | SF | 5 | 9 | 0 | 86 | 120 | -34 | 171 |
| Marshawn Lynch | SF | 4 | 3 | 0 | 85 | 87 | -2 | 44 |
| Derrick Henry | ATL | 1 | 2 | 1 | 80 | 75 | 5 | 41 |
| Philadelphia D | SD | 3 | 9 | 1 | 78 | 108 | -30 | 104 |
| Kerryon Johnson | DEN | 3 | 4 | 0 | 73 | 75 | -2 | 54 |
| Graham Gano | SH | 4 | 7 | 1 | 72 | 82 | -10 | FA |
| Damien Williams | DEN | 2 | 1 | 0 | 66 | 57 | 9 | FA |
| Minnesota D | CTR | 2 | 5 | 0 | 58 | 70 | -12 | 95 |
| Calvin Ridley | LAB | 4 | 2 | 0 | 56 | 68 | -12 | FA |
| Kirk Cousins | SD | 1 | 1 | 0 | 55 | 63 | -8 | 70 |
| Evan Engram | SF | 3 | 1 | 0 | 54 | 31 | 23 | 49 |
| Tyler Lockett | DEN | 1 | 4 | 0 | 54 | 99 | -45 | FA |
| Dak Prescott | TB | 0 | 1 | 1 | 53 | 57 | -4 | 127 |
| T.J. Yeldon | ND | 1 | 3 | 0 | 51 | 66 | -15 | FA |
| Demaryius Thomas | ATL | 2 | 5 | 0 | 51 | 104 | -53 | 32 |
| Jimmy Garoppolo | ATL | 1 | 1 | 0 | 50 | 81 | -31 | 113 |
| Royce Freeman | TB | 1 | 4 | 0 | 50 | 84 | -34 | 40 |
| Greg Olsen | SF | 5 | 3 | 0 | 50 | 90 | -40 | 65 |
| C.J. Anderson | SD | 1 | 5 | 1 | 49 | 104 | -55 | 110 |
| Seattle D | CTR | 3 | 0 | 1 | 48 | 23 | 25 | FA |
| Cooper Kupp | SD | 3 | 1 | 0 | 48 | 38 | 10 | 142 |
| Carlos Hyde | LAB | 2 | 2 | 0 | 47 | 71 | -24 | 76 |
| Giovani Bernard | FW | 1 | 1 | 0 | 44 | 34 | 10 | 123 |
| Baltimore D | CTR | 3 | 4 | 0 | 44 | 53 | -9 | 109 |
| Elijah McGuire | ANC | 1 | 2 | 0 | 44 | 72 | -28 | FA |
| Tyrod Taylor | LAB | 0 | 2 | 0 | 44 | 73 | -29 | 121 |
| Indianapolis D | DEN | 2 | 4 | 1 | 43 | 46 | -3 | FA |
| Marvin Jones | SD | 0 | 5 | 1 | 40 | 97 | -57 | 58 |
| Robbie Gould | SF | 1 | 4 | 0 | 38 | 46 | -8 | 176 |
| Nick Mullens | ND | 0 | 2 | 0 | 38 | 92 | -54 | FA |
| Jay Ajayi | DEN | 0 | 2 | 0 | 33 | 41 | -8 | 30 |
| Allen Robinson | SH | 0 | 5 | 0 | 33 | 125 | -92 | 45 |
| Spencer Ware | DEN | 1 | 1 | 0 | 32 | 31 | 1 | 159 |
| Austin Ekeler | ANC | 1 | 2 | 0 | 31 | 35 | -4 | 167 |
| Austin Hooper | DEN | 1 | 3 | 0 | 31 | 58 | -27 | FA |
| Nelson Agholor | ND | 1 | 2 | 0 | 30 | 38 | -8 | 161 |
| Gus Edwards | SD | 0 | 3 | 0 | 30 | 71 | -41 | FA |
| Zach Zenner | DEN | 1 | 1 | 0 | 29 | 47 | -18 | FA |
| Mitchell Trubisky | LAB | 1 | 0 | 0 | 28 | 12 | 16 | 150 |
| Ian Thomas | SH | 0 | 3 | 0 | 28 | 47 | -19 | FA |
| Peyton Barber | LAB | 0 | 3 | 0 | 28 | 78 | -50 | 147 |
| Courtland Sutton | SD | 2 | 2 | 0 | 26 | 28 | -2 | FA |
| Jack Doyle | ND | 2 | 3 | 0 | 25 | 39 | -14 | 92 |
| Alshon Jeffery | SH | 2 | 0 | 0 | 24 | 12 | 12 | 60 |
| Carolina D | CTR | 1 | 1 | 1 | 23 | 14 | 9 | 174 |
| Denver D | DEN | 0 | 3 | 1 | 23 | 59 | -36 | FA |
| D.J. Moore | SD | 0 | 3 | 1 | 22 | 99 | -77 | FA |
| Justin Jackson | ANC | 1 | 1 | 0 | 21 | 16 | 5 | FA |
| Nyheim Hines | ND | 0 | 2 | 0 | 21 | 67 | -46 | FA |
| Kenyan Drake | SH | 1 | 5 | 0 | 21 | 95 | -74 | 31 |
| Corey Davis | CTR | 1 | 1 | 0 | 20 | 24 | -4 | 78 |
| Ty Montgomery | SD | 2 | 1 | 0 | 19 | 12 | 7 | 153 |
| Washington D | DEN | 1 | 3 | 0 | 19 | 34 | -15 | FA |
| Doug Martin | SF | 1 | 0 | 0 | 18 | 9 | 9 | 126 |
| Buffalo D | SD | 1 | 2 | 1 | 18 | 31 | -13 | FA |
| Sammy Watkins | LAB | 1 | 3 | 0 | 18 | 31 | -13 | 80 |
| Joe Flacco | CTR | 0 | 1 | 0 | 18 | 36 | -18 | FA |
| Adam Humphries | SD | 0 | 3 | 0 | 17 | 64 | -47 | FA |
| Kendrick Bourne | SF | 1 | 0 | 0 | 16 | 2 | 14 | FA |
| Antonio Callaway | SF | 0 | 3 | 0 | 16 | 62 | -46 | FA |
| Jeff Wilson | ATL | 1 | 0 | 0 | 14 | 13 | 1 | FA |
| Jaylen Samuels | ND | 0 | 1 | 0 | 13 | 14 | -1 | FA |
| LeGarrette Blount | DEN | 0 | 2 | 1 | 13 | 74 | -61 | 134 |
| Detroit D | FW | 0 | 1 | 0 | 12 | 15 | -3 | 170 |
| Jordy Nelson | SD | 0 | 1 | 0 | 12 | 16 | -4 | 101 |
| New York Giants D | SH | 0 | 3 | 0 | 12 | 26 | -14 | FA |
| Theo Riddick | DEN | 1 | 0 | 0 | 10 | 3 | 7 | FA |
| Vance McDonald | TB | 2 | 0 | 0 | 10 | 5 | 5 | FA |
| Cairo Santos | ATL | 1 | 0 | 0 | 10 | 9 | 1 | FA |
| Mike Badgley | SH | 1 | 2 | 0 | 10 | 13 | -3 | FA |
| Philip Rivers | ANC | 0 | 1 | 0 | 10 | 28 | -18 | 108 |
| Tyler Eifert | SF | 0 | 1 | 0 | 9 | 18 | -9 | 155 |
| Dallas D | ND | 0 | 1 | 0 | 9 | 19 | -10 | FA |
| Latavius Murray | ATL | 0 | 0 | 1 | 8 | 8 | 0 | FA |
| Benjamin Watson | SF | 1 | 1 | 0 | 6 | 10 | -4 | FA |
| Tennessee D | ATL | 1 | 0 | 0 | 5 | 2 | 3 | FA |
| Jamison Crowder | CTR | 1 | 0 | 0 | 5 | 4 | 1 | 131 |
| Delanie Walker | CTR | 0 | 1 | 0 | 5 | 10 | -5 | 69 |
| C.J. Uzomah | SF | 0 | 1 | 1 | 5 | 23 | -18 | FA |
| Keelan Cole | ATL | 0 | 1 | 0 | 5 | 34 | -29 | FA |
| Arizona D | ND | 1 | 0 | 0 | 4 | 1 | 3 | FA |
| Dion Lewis | ATL | 0 | 0 | 1 | 4 | 4 | 0 | 72 |
| Devonta Freeman | SD | 0 | 1 | 0 | 4 | 5 | -1 | 17 |
| Quincy Enunwa | FW | 0 | 1 | 0 | 4 | 10 | -6 | FA |
| Mike Davis | LAB | 0 | 1 | 0 | 4 | 32 | -28 | FA |
| Isaiah Crowell | DEN | 0 | 1 | 0 | 3 | 17 | -14 | 67 |
| Chris Boswell | SH | 0 | 2 | 0 | 3 | 18 | -15 | 138 |
| Robby Anderson | ANC | 0 | 1 | 0 | 2 | 16 | -14 | 103 |
| John Brown | ATL | 1 | 1 | 0 | 2 | 17 | -15 | FA |
| Alfred Morris | LAB | 0 | 2 | 0 | 2 | 20 | -18 | FA |
| Doug Baldwin | ATL | 0 | 1 | 1 | 2 | 21 | -19 | 37 |
| Ryan Grant | LAB | 0 | 1 | 0 | 2 | 42 | -40 | FA |
| Geronimo Allison | SD | 0 | 1 | 0 | 1 | 7 | -6 | FA |
| Jordan Wilkins | ND | 0 | 1 | 0 | 1 | 15 | -14 | 172 |
| Chris Hogan | LAB | 0 | 1 | 0 | 1 | 20 | -19 | 73 |
| Jamaal Williams | CTR | 0 | 1 | 0 | 1 | 28 | -27 | 96 |
| DeVante Parker | TB | 0 | 1 | 0 | 0 | 1 | -1 | 168 |
| New Orleans D | LAB | 0 | 1 | 0 | 0 | 13 | -13 | 160 |
| Jesse James | ND | 0 | 1 | 0 | 0 | 15 | -15 | FA |
| O.J. Howard | SD | 0 | 2 | 0 | 0 | 19 | -19 | 130 |
| 778 | 778 | 76 | 23994 | 23994 | 0 | |||
| 1632 |